Differential Control of Luteinizing Hormone and Follicle-Stimulating Hormone Secretion by Luteinizing Hormone-Releasing Hormone Pulse Frequency in Man*
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چکیده
منابع مشابه
Control of gonadotropin secretion by follicle-stimulating hormone-releasing factor, luteinizing hormone-releasing hormone, and leptin.
Fractionation of hypothalamic extracts on a Sephadex G-25 column separates follicle-stimulating hormone-releasing factor (FSHRF) from luteinizing hormone-releasing hormone (LHRH). The FSH-releasing peak contained immunoreactive lamprey gonadotropin-releasing hormone (lGnRH) by radioimmunoassay, and its activity was inactivated by an antiserum specific to lGnRH. The identity of lGnRH-III with FS...
متن کاملHormonal responses to synthetic luteinizing hormone and follicle stimulating hormone-releasing hormone in man.
The effects of the gonadotrophin-releasing hormone, synthetic decapeptide luteinizing hormone/follicle stimulating hormone-releasing hormone (LH/FSH-RH), have been studied in 18 normal men and five women in the follicular phase of their menstrual cycle. Rapid and dose-dependent (25 to 100 mug) increases in serum immunoreactive LH were seen, which reached a peak 20 to 30 minutes after a rapid in...
متن کاملUse of clomiphene and luteinizing hormone/follicle stimulating hormone-releasing hormone in investigation of ovulatory failure.
A luteinizing hormone/follicle-stimulating hormone-releasing hormone (LH/FSH-RH) test was performed in 70 women with amenorrhoea or anovulatory infertility, or both, and a clomiphene stimulation test was also performed in 24 of these patients. Most patients responded to LH/FSH-RH with significant increases in LH and FSH. In women with gonadal dysgenesis or premature ovarian failure exaggerated ...
متن کاملInteraction of estradiol and luteinizing hormone releasing hormone on follicle stimulating hormone release in cattle.
To study the mechanism by which estradiol induces a preovulatory surge of follicle stimulating hormone (FSH), we concluded experiments designed to determine: (1) the time course of change in luteinizing hormone releasing hormone (LHRH)-induced FSH release after estradiol in vivo, and (2) whether LHRH is required to trigger the FSH surge. Steers were given 1 microgram LHRH at 20-min intervals fo...
متن کاملIsolation of the luteinizing hormone and follicle-stimulating hormone-releasing hormone from porcine hypothalami.
A new procedure is described for the isolation on a preparative scale of a hypothalamic decapeptide which stimulates the release of both luteiaizing hormone (LH) and folliclestimulating hormone (FSH) from the pituitary. The isolation was achieved mainly by countercurrent distribution. The yield from 240,000 porcine hypothalami was 11.4 mg. Thin layer chromatography and electrophoresis showed th...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1987
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem-64-4-675